姓名:  程妮

所属部门:yl6809永利

职称：教授

荣誉:   永利集团青年学术英才 ；博士生导师

电子邮件: chengni@nwu.edu.cn　

研究方向：功能食品的研究与开发；蜂产品质量安全控制及开发

一、个人简介

程妮：女，博士，教授，博士生导师，永利集团青年学术英才，陕西省蜂业协会副秘书长、陕西省营养学会理事、中国养蜂学会蜂产品专委会委员。主要开展功能食品的研究与开发，蜂产品质量安全控制及产品开发等方面的研究工作。主持国家自然基金1项，国家重点研发计划子课题1项，中央引导地方科技专项合作项目1项，主持陕西省重点研发计划4项，西安市农业科技攻关1项，榆林市产学研项目1项，主持陕西省电分析化学重点实验室开放基金1项。参与国家自然科学基金5项，省部级项目10项，参与横向科研项目8项。在《Food & Function》、《Food Bioscience》、《Food Research International》、《Food and Chemical Toxicology》、《Food control》、《Food Chemistry》、《食品科学》等国内外期刊上发表科学论文60余篇，其中SCI收录50余篇。

二、研究成果

论文：

1. Minghao Chen, Xiaomiao Yang, Zhelin Ji, Haoan Zhao, Ni Cheng*, Wei Cao*. Combined treatment of drying, ethanol, and cold plasma for bee pollen: Effects on microbial inactivation and quality attributes. Food Bioscience, 2024, 57, 103542.

2. Sinan Chen, Yifei Xu, Ni Cheng*, Feng Li, Haoan Zhao, Naisheng Bai, Hesham R. EI-Seedi, Wei Cao. Mitigation of DSS-Induced Colitis Potentially via Th1/Th2 Cytokine and Immunological Function Balance Induced by Phenolic-Enriched Buckwheat (Fagopyrum esculentum Moench) Bee Pollen Extract. Foods, 2022, 11(9), 1293.

3. Yuanyuan Xu, Xirong Cao, Haoan Zhao, Erlin Yang, Yue Wang, Ni Cheng*, Wei Cao. Impact of Camellia japonica Bee Pollen Polyphenols on Hyperuricemia and Gut Microbiota in Potassium Oxonate-Induced Mice. Nutrients, 2021, 13, 2665.

4. Sinan Chen, Xiaochao Wang, Ni Cheng*. Ultrasound-assisted ethanol extraction of Actinidia

arguta pollen possesses antioxidant activity and protects DNA from oxidative damage. Journal of Food Biochemistry, 2021, 00: e13603.

5. Ni Cheng*, Sinan Chen, Xinyan Liu, Haoan Zhao, Wei Cao*.Impact of SchisandraChinensis Bee Pollen on Nonalcoholic Fatty Liver Disease and Gut Microbiota in HighFat Diet Induced Obese Mice. Nutrients, 2019, 11(2), 346.

6. Sinan Chen, Haoan Zhao, Ni Cheng*, Wei Cao*. Rape bee pollen alleviates dextran sulfate sodium (DSS)-induced colitis by neutralizing IL-1β and regulating the gut microbiota in mice. Food Research International, 2019, 122, 241-251.

7. Ni Cheng*, Haoan Zhao, Sinan Chen, Wei Cao*.Jujube honey induces apoptosis in human hepatocellular carcinoma HepG2 cell via DNA damage, p53 expression, and caspase activation. Journal of Food Biochemistry, 2019, 43: e12998.

8. Haoan Zhao＃,  Ni Cheng＃,  Qian Wang, Wenqi Zhou,  Caiyun Liu,  Xinyan Liu, Sinan Chen,  Daidi Fan Wei Cao. Effects of honey-extracted polyphenols on serum antioxidant capacity and metabolic phenotype in rats. Food & Function, 2019, 10, 2347-2358.

9. Haoan Zhao＃, Ni Cheng＃, Wenqi Zhou, Sinan Chen, Qian Wang, Hui Gao, Xiaofeng Xue,Liming Wu,* and Wei Cao*. Honey Polyphenols Ameliorate DSS-Induced Ulcerative Colitis via Modulating Gut Microbiota in Rats. Molecular Nutrition & Food Research, 2019, 63, 1900638.

10. Haoan Zhao, Ni Cheng, Liangliang He, Guoxia Peng, Qingqing Liu, Tianchen Ma, Wei Cao*. Hepatoprotective effects of the honey of ApisceranaFabriciuson bromobenzene-induced liver damage in mice. Journal of Food Science, 2018, 83 (2): 509-516.

11. Ni Cheng, Yuan Wang, Wei Cao*. The Protective Effect of Whole Honey and Phenolic Extract on Oxidative DNA Damage in Mice Lymphocytes Using Comet Assay, Plant Foods for Human Nutrition, 2017, 72, 388-395.

12. Haoan Zhao, Ni Cheng, Liangliang He, Guoxia Peng, XiaofengXue, Liming Wu, Wei Cao*. Antioxidant and hepatoprotective effects of A. cerana honey against acute alcohol-induced liver damage in mice. Food Research International, 2017, 101, 35-44.

13. Haoan Zhao, Ni Cheng*, Hui Gao, Wei Cao. Survey of Chloramphenicol in Honeys from China. Journal of Residuals Science & Technology, 2016, 13, S163-S167.

14. Cheng Ni, Wu Liming, Zheng Jianbin, Cao Wei. Buckwheat Honey Attenuates Carbon Tetrachloride-Induced Liver and DNA Damage in Mice，Evidence-Based Complementary and Alternative Medicine, 2015, 10: 1-10.

15. Cheng Ni , Juan Zhou, Wang Meng, Cao Wei, The Protection of the Extracts of Sour Jujube (Ziziphusjujuba var. spinosa (Bunge) Hu) on DNA Damage Caused by Oxidative Stress，Journal of Pure and Applied Microbiology，2015，9：249-260.

16. Ni Cheng, Bing Du, Yuan Wang, Hui Gao, Wei Cao*, Jianbin Zheng*, Fan Feng. Antioxidant properties of jujube honey and its protective effects on chronic alcohol-induced liver damage in mice, Food & Function, 2014, 5:900-908.

17. Ni Cheng, Yuan Wang, Hui Gao, Jialing Yuan, Fan Feng, Wei Cao*, Jianbin Zheng*. Protective effect of extract of Crataegus pinnatifida pollen DNA damage response to oxidative stress, Food and Chemical Toxicology, 2013, 59: 709-714.

18. Ni Cheng, Naiyan Ren, Hui Gao, Xingsheng Lei, Jianbin Zheng*, Wei Cao*. Antioxidant and hepatoprotective effects of Schisandra chinensis pollen extract on CCl4-Induced acute liver damage in mice, Food and Chemical Toxicology, 2013, 55: 234-240.

19. Ni Cheng, Hui Gao, Jianjun Deng, Bini Wang, Ruihan Xu, Wei Cao*. Removal of chloramphenicol by macroporous adsorption resinsin Honey-a novel approach on reutilization of antibiotics contaminated honey, Journal of Food Science, 2012, 77(9): 169-172.

20. Yuan Wang, Dan Li, Ni Cheng, Hui Gao, XiaofengXue, Wei Cao*, Liping Sun*. Antioxidant and hepatoprotective activity of vitex honey against paracetamol in duced liver damage in rats, Food & Function, 2015, 6,2339-2349.

21. Ruihan Xu, Ni Cheng*, Wei Huang, Hui Gao, Jianjun Deng, Wei Cao*. Effects of the processing steps on parathion levels during honey production and parathion removal by macroporous adsorption resins, Food Control, 2012, 23, 234-237.

22. Qi Jia, Shifeng Yu, Ni Cheng, Liming Wu, Jiajia Jia; XiaofengXue,Wei Cao*. Stability of nitrofuran residues during honey processing and nitrofuran removal by macroporous adsorption resins, Food Chemistry, 2014, 162:110-116.

23. Jinmei Wang, Xiaojing Du, Ni Cheng, XiaofengXue, Lanzhen Chen, Jing Zhao*, Jianbin Zheng, Wei Cao*. Identification of acacia honey adulteration with rape honey using Liquid chromatography–electrochemical detection and chemometrics, Food Analytical Methods, 2014, 7(10): 2003-2012.

24. Juan Zhou, Zhirong Suo, Pinpin Zhao, Ni Cheng, Hui Gao, Jing Zhao*, Wei Cao*. Jujube honey from China: Physicochemical characteristics and mineral contents, Journal of Food Science, 2013, 78(3): C387-394.

25. Du Xiaojing, Yan Wu, Han Zhou, Ni Cheng, Yan Liang, Jianbin Zheng, Wei Cao*. Development of a HPLC–ECD method for the simultaneous determination of three synthetic estrogens in milk, Analytical Methods, 2013, 5: 2822-2826.

26. Juan Zhou, Peng Li, Ni Cheng, Hui Gao, Bini Wang, Yahui Wei, Wei Cao*. Protective effects of buckwheat honey on DNA damage induced by hydroxyl radicals, Food and Chemical Toxicology, 2012, 50: 2766-2773.

27. Hui Gao, Ni Cheng, Juan Zhou, BiNi Wang, JianJun Deng, Wei Cao*. Antioxidant activities and phenolic compounds of date plum persimmon (Diospyros lotus L.) fruits, Journal of Food Science and Technology, 2011, 47(1): 1-7.

28.Wei Cao, Haifeng Liu, Ni Cheng, Hui Gao, Bini Wang, Jianbin Zheng. LC with electrochemical detection for analysis of caffeic acid and caffeic acid phenyl ester in propolis. Chromatographia, 73, 411-414, 2011.

29. 段倩倩, 程妮*, 赵丞, 曹炜. 油菜蜂花粉发酵工艺及生物活性研究[J]. 食品与发酵工业，2023, 49(19): 135-142.

30. 王小超, 程妮*, 段倩倩, 赵丞, 徐元元, 陈思南, 曹炜. 体外消化和结肠发酵对蜂花粉酚类化合物及抗氧化活性的影响. 食品与发酵工业, 2022, 48(6):141-146.

31. 王悦, 徐元元, 杨二林, 程妮*. 酶解结合高剪切破壁技术对蜂花粉酚类物质及抗氧化活

性的影响. 农业工程学报, 2021, 37(2): 313-320.

32. 徐元元, 王悦, 杨二林,王小超，赵浩安，程妮*，曹炜. 3种蜂花粉酚类化合物组成及抗氧化活性研究,永利集团学报（自然科学版）, 2021, 51(2): 303-313.

33. 陈思南, 王心怡, 李梦婷, 何亮亮, 王齐蕾, 王郭娇, 王卫东, 曹炜, 程妮*. 五味子蜂花粉不同萃取物对小鼠肝脏脂质过氧化及DNA氧化损伤的作用. 食品科学, 2019, 40 (11): 146-151.

34. 程妮，杜雯玺，丰凡，曹炜，蜂花粉中酚类物质的分布及抗氧化活性，食品与发酵工业，2013，（11）：163-166。

35. 程妮，王毕妮，邓建军，高慧，曹炜，不同产地油菜蜂花粉抗氧化活性比较研究，食品科学，2011，（21）：34-36。

36. 程妮，高慧，王毕妮，邓建军，刘媛媛，曹炜，松花粉提取物抗氧化活性及其酚类化合物的研究，食品与发酵工业，2011，（05）：118-122。

37. 程妮，高慧，王毕妮，李铮，曹炜，蜂王浆对猪肉保鲜作用的研究，食品与发酵工业，2010，（08）：165-167。

专著

《蜂产品深加工技术》, 参编, 中国轻工业出版社, 2011.

《中蜂饲养技术》, 副主编, 永利集团出版社, 2019.

《畜产食品工艺学》, 参编, 中国农业出版社, 2019.

发明专利：

1.一种蜂花粉制剂及制备方法和在预防 DNA 氧化损伤中的应用，已授权：ZL201810055064.X.第一发明人

2.一种苦荞黄酮的包埋方法，已授权：ZL 20310355787.9，第一发明人

3. 一种从枣花蜜中提取、纯化酚类化合物的方法,已转化: ZL201510890084.5，第一发明人

4.一种蜂花粉抗氧乳及其制备方法, 已转化: ZL 201510889965.5，第一发明人

5. 一种基于食品加工用的包装封口装置，已授权，ZL202220941923.7，第一发明人

6. 一种用于饼干原料加工的快读研磨设备，已授权，ZL202220929912.7，第一发明人

7. 五味子蜂花粉有效部位及其在预防肝脏损伤中的应用, 已授权: ZL 201310083521.3，第二发明人

8. 一种采用真空冷冻干燥制备猕猴桃果脯的方法,已授权: ZL 201210225986.3，第三发明人

9. 洋槐蜜中掺有油菜蜜的鉴别方法, 已授权:ZL 201310647702.4，第四发明人

10. 褪黑素用于果蔬保鲜的应用及保鲜方法,已授权:ZL 201410108940.2，第三发明人

11. 一种鉴别过度热加工枣花蜜的方法，已授权：ZL201710189698.X，第三发明人

12. 蜂胶有效部位及其复方制品和应用，ZL 201710315058.9,2020年5月，排名第三；

13. 一种蜂蜜中硝基咪唑类和喹诺酮类药物残留脱除方法，ZL 201710204362.6, 2020年3月，排名第三；

研究课题

主持的项目

1. 中蜂现代养殖模式创建与应用（2022YFD1600205）, 2022.11-2026.10. 国家重点研发计划项目子课题，在研

2. 佳县枣花蜜生产及高值化利用关键技术研发 (2023ZY1-CGZY-06), 2023.1-2024.12. 中央引导地方科技专项合作项目，在研

3.蜂花粉破壁关键技术及产品开发（2021NY-128）,2021.1-2022.12，陕西省科技厅重点研发计划一般项目，已结题

4. 五味子蜂花粉高抗氧化酚类及其对细胞色素C介导的细胞氧化损伤保护机制研究（31602103），2017.01-2019.12，国家自然基金，已结题

5. 成熟蜂蜜生产关键技术及生物活性研究(2017NY-073), 2017.01-2019.12，陕西省科技厅，已结题

6. 陕北小米深加工及副产物综合高效利用技术, 榆林市产学研合作项目，已结题

7. 蜂花粉抗氧化活性成份提取及产品开发，陕西省科技厅农业攻关项目，已结题

8. 一种蜂花粉抗氧化乳及乳粉的研制，陕西省科技厅农业攻关项目，已结题

9. 苦荞抗氧化乳的研究与开发，西安市科技创新支撑计划，已结题

获奖情况

1.第十三届陕西省自然科学优秀学术论文奖三等奖（排名第一）

2.2017年陕西省科技工来源：yl6809永利创新创业大赛铜奖（排名第二）